Best Mouse Poisons
9 minutes to read | Updated for 2018
Sometimes you reach a point where you feel you have tried everything. Maybe you have attempted traps– perhaps you even got a cat to keep the rodents away.
An excellent method for getting pesky mice and rats out of the home is to use poison. This is an effective way of driving the population down and keeping them out of your home for good.
In this article, we are reviewing the four best mouse poisons of 2018 that you can purchase today.
Top Rated Mouse Poisons








Last update on 2019-12-12 / Affiliate links / Images from Amazon Product Advertising API
What’s In This Guide
Best Overall–Neogen Rodenticide 45-Pack Ramik Rat and Mouse Bait Pail
Last update on 2019-12-12 / Affiliate links / Images from Amazon Product Advertising API
This poison can be used in all weather conditions and is effective indoors and outdoors. You use this bait to kill both mice and rats. The bait has a fish-based flavor and an abundance of protein to attract rodents.
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Inside the pail is a bunch of smaller individual use bait packs. Each pack has 45 small pieces of bait that you can use throughout the home to attract the rodents.
The great thing about this product is that the rodents will find the bait, eat it and because its a blood thinner they will become very thirsty. This bait causes them to go outside often to drink water, so they usually die outside the home, so you do not have to be bothered by a messy cleanup or odor.
This bait is very attractive to the mice and rats, so it is an effective way of killing off the population quickly and ridding yourself of the problem.
Product Features
- Four-pound container
- Has 45 individual bait packs inside
- Attractive formula draws attention quickly
PRO
- Large container can take out a massive infestation
- Very attractive formula
- Mice often take the bait with them to the nest and kill off the rest
- Works fast
CON
- Keep away from pets; this does not come in a tamper-proof container. You have to spread it across the floor.
Best Runner-Up–Farnam Just One Bite Bait Chunks
Last update on 2019-12-12 / Affiliate links / Images from Amazon Product Advertising API
These large sized bait chunks are a very effective method of clearing out a big rodent infestation. The bait is capable of killing any rodent and can be used indoors and outdoors.
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The bait comes in large blocks that can get placed as is or crushed up and sprinkled in trouble areas like behind appliances. The blocks come in an eight-pound container and have a powerful formula that attracts rodents quickly.
Within a few days, you will start noticing dead rodents all over the place, so it is important to temporarily put any pets somewhere else, so they do not get sick from eating or playing with the mice.
Even though the bait works very well, it’s still essential to close off the access points from the exterior of the house.
Product Features
- Eight-pound container
- Can be used indoors or outdoor
- Effective treatment for all types of rodents
PRO
- Highly effective method of treating a rodent problem
- Blocks do not get easily moved and last a long time
- Can be crushed up for hard to reach places
- Formula attracts and kills quickly
CON
- Highly dangerous to be around pets, the formula has the potential to kill anything that eats it.
Best Pet-Safe Poison–EcoClear Products RatX All-Natural Non-Toxic Rat and Mouse Killer Pellets
Last update on 2019-12-11 / Affiliate links / Images from Amazon Product Advertising API
This mouse poison is non-toxic and 100% safe around children, pets, and other wildlife. The formula is designed to kill the mice humanely. It kills them quickly after eating it only once, so they do not suffer slowly.
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The poison also does not cause any secondary poisoning and cannot contaminate and food or crops that the rodents come in contact with. If the poison does not get eaten, it is completely biodegradable and has no negative impact on the environment.
This product only works on mice and rats; it will not work on any other pest because of their complex digestive systems. The total amount of time from when the mice ingest the poison until their death is typically no longer than four days. They swallow the poison and retreat to their burrows to sleep.
Product Features
- Comes in a 1lb, 3lb, or 25lb bag
- 100% naturally made and non-toxic
- Safe around pets and children
- No negative environmental impact
PRO
- Humane way of killing mice and rats
- 100% non-toxic
- Completely safe around pets and children
- Effective at killing mouse population
- No negative environmental impact
CON
- Can take a long time to attract the rodents
Best Poison Packs–Neogen Rodenticide Havoc Mouse and Rat Killer
Last update on 2019-02-10 / Affiliate links / Images from Amazon Product Advertising API
These pellet packs are an effective method for killing mice and rats in your home. The packs can be used in all weather conditions and are capable of killing off your entire infestation in only one feeding. This makes the process quicker and more humane.
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The poison packs are also somewhat safer around pets and children because you do not have to remove the bait from the bag for it to be effective. The mice will chew right through the pack to get to the bait and typically eat the entire pack in one sitting.
These packs also contain some of the most potent anticoagulants on the market so when the rodents do eat the poison they will not be stuck rotting somewhere in your house. They turn to dust within days of ingesting the poison. It is still a good idea to keep these packs away from pets.
Product Features
- Comes in 10, 20, and 40 packs
- Individual packs can get placed throughout the house
- Bait stays inside the pack
- Ingredients prevent rat and mice from rotting when they die
PRO
- Great method for treating infestations that get spread across the house
- Safer than some methods around pets and kids
- Kills population quickly
- Anticoagulants prevent rotting rodent carcasses
CON
- Mixed reviews about the mice chewing through the pack

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read moreWhy Do You Have a Mouse/Rat Issue?
Mice and rats enter a home for a variety of reasons–some of these are out of your control, and some are within your control. If you have pets, you probably leave out food bowls on the floor, and this is just one way that mice become attracted to your home.
Here are some other things that bring rodents into your house:
- Bird feeders
- Garbage bags kept inside the house
- Gardens running along the exterior of the home
- Pet feces that is not cleaned up
- Crumbs on the side or behind appliances
In addition to all of the human things that we do to attract rodents, there are also structural issues with your home that could be opening you up to a rodent infestation. Here are a few examples of easy access points for mice into your home:
- Cracks and openings in the foundation
- Wires that run from the ground to the roof
- Open pipes
- Gutters
- Trees that rub up against the house near windows or doors
Taking a look at these areas of your home also give you a good idea of where to place the bait. If you find an abundance of droppings behind the refrigerator where there is a lot of crumbs, leave them there but place the bait there as well. Knowing where the trouble spots are in your home gives you a better chance of eliminating the population.
Single Feeding Poison vs. Multi-Feeding Poison
There are two different types of baits, and they each have their benefits and downsides. We are going to take a look at these below.
Single Feed
These baits are much stronger and toxic compared the multi-feeding baits. You often cannot find these in stores, and professional pest control companies use them. Since the bait is so strong, it’s highly toxic if consumed by anything. If you decide to use this kind of poison experts, suggest taking your pets on a temporary vacation so you can ensure they do not get anywhere near the poison until you have taken care of the problem.
When using this kind of bait also be sure you know the antidote and you do not get rid of the container until you know all the bait got consumed by the rodents only.
Multi-Feed
This bait is less toxic and forces the rodents to eat it more than once for it to be successful. The rodents will typically come back to the bait for at least a week before it affects them. The multi-feed strategy requires patience, but it is just as useful as the single feed method. Because the poison is less toxic, there is less risk associated with it getting consumed by your pets and children. Unless it is entirely non-toxic, you still want to know the antidote and take the cautionary steps.
Over time rodents have developed an immunity to a lot of multi-feed poisons so once they taste it they only take a little bit and it is not enough to kill them. Instead, it just makes them sick and causes them to vomit. Your home situation will determine what type of bait method works best for you.
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